Through the direct testimony of the Indians, the phenomenon of acculturation suffered by the Otomí minority of the Mezquital Valley, one of the poorest rural areas of the state of Hidalgo, in Mexico, is analyzed. It tries to show a broader problem that encomes a large part of the Continent; how other peoples, other ethnic groups, are exterminated with all kinds of mechanisms, from brutal repression to the most sophisticated cultural penetration.